Diuretics — commonly called water pills — are medicines that increase urine production by acting on the kidneys to reduce fluid retention in the body. They are used to treat hypertension (high blood pressure), oedema (fluid swelling) caused by heart failure, liver cirrhosis, or kidney disease, and certain electrolyte disorders. All prescription diuretics require a valid prescription.
Diuretic Drug Classes
Thiazide diuretics — hydrochlorothiazide (HCTZ) is the most widely prescribed thiazide. They act on the distal convoluted tubule of the kidney to inhibit sodium-chloride reabsorption, promoting water excretion. First-line for uncomplicated hypertension in many guidelines.
Loop diuretics — furosemide (Lasix) inhibits the Na-K-2Cl transporter in the thick ascending limb of the loop of Henle, producing a powerful and rapid diuresis. Used for acute pulmonary oedema, heart failure, and resistant hypertension.
Potassium-sparing diuretics — triamterene acts on the collecting duct to block sodium channels without wasting potassium. Often combined with HCTZ (as Dyazide or Maxzide) to offset potassium loss from thiazides.
Diuretics Covered at Lucas Clinic
- Hydrochlorothiazide (HCTZ) — thiazide diuretic for hypertension and oedema
- Lasix (Furosemide) — loop diuretic for heart failure and fluid overload
- Triamterene — potassium-sparing diuretic, often combined with HCTZ
Disclaimer: For informational purposes only. All diuretics require a prescription. Consult a licensed healthcare professional. See our full disclaimer.